Emergent BioSolutions Inc. products

ACAM2000, (Smallpox (Vaccinia) Vaccine, Live) is a live, vaccinia virus smallpox vaccine licensed in the U.S. by the Food and Drug Administration for active immunization against smallpox disease for persons determined to be at high risk for smallpox infection. It was developed under a contract with the U.S. Centers for Disease Control and Prevention (CDC).

ANTHRASIL is a clear to opalescent sterile liquid of purified immune globulin G (IgG) fraction of human plasma containing polyclonal antibodies that bind the protective antigen (PA) component of Bacillus anthracislethal and edema toxins.ANTHRASIL is prepared using plasma collected from healthy, screened donors who were immunized with BioThrax®(Anthrax Vaccine Adsorbed) to achieve high titers of anti-anthrax antibody (meeting minimum potency specifications) and purified by an anion-exchange column chromatography method.Product potency, as determined by the Toxin Neutralization Assay, is expressed in units (U) by comparison to the Centers for Disease Control and Prevention (CDC) standard AVR414.A single use 50 mL vial contains anti-anthrax antibodies at ≥60 Units by Toxin Neutralization Activity (TNA), regardless of fill volume.

BAT [Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G) – (Equine)] is a sterile solution of F(ab`)2 and F(ab`)2-related antibody fragments prepared from plasma obtained from horses that have been immunized with a specific serotype of botulinum toxoid and toxin. To obtain the final heptavalent product, the seven antitoxin serotypes are blended. BAT is supplied in a 50 milliliter(mL) vial size. BAT is administered intravenously.The manufacturing process for each antitoxin type includes cation-exchange chro

This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions.

You and your family members or caregivers should read this Patient Information leaflet before an opioid emergency happens. This information does not take the place of talking with yourhealthcare provider about your medical condition or your treatment

Raxibacumab is indicated for the treatment of adult and pediatric patients with inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs. Raxibacumab is also indicated for prophylaxis of inhalational anthrax when alternative therapies are not available or are not appropriate.

The Reactive Skin Decontamination Lotion Kit is intended to remove or neutralize chemical warfare agents and T-2 Toxin from the skin.

VAXCHORA is a vaccine indicated for active immunization against disease caused by Vibrio cholerae serogroup O1 in adults 18 through 64 years of age traveling to cholera-affected areas.

Blood glucose measurement in patients receiving VIGIV must be done with a glucose-specific method (monitor and test strips) to avoid interference by maltose contained in VIGIV. Glucose dehydrogenase pyrroloquinolinequinone (GDH-PQQ) or glucose-dye-oxidoreductase method (monitor and test strips) must not be used for blood glucose testing in patients receiving VIGIV, since maltose in IGIV products has been shown to give falsely high blood glucose levels in these testing systems. This could result in the inappropriate administration of insulin, resulting in life-threatening hypoglycemia. Cases of true hypoglycemia may go untreated if the hypoglycemic state is masked by falsely elevated glucose readings.Carefully review t he product information of the blood glucose testing system, including that of the test strips, to determine if the system is appropriate for use with maltose-containing parenteral products [see 5.3 Blood Glucose Monitoring].

Vivotif (Typhoid Vaccine Live Oral Ty21a) is a live attenuated vaccine for oral administration only. Thevaccine contains the attenuated strainSalmonella typhiTy21a (1,2).