Expo Process Analytics products

The FFSim™ Feed Frame Simulator from Expo Process Analytics is an advanced laboratory-scale simulation tool designed to enhance pharmaceutical process development. It provides a modern alternative to traditional scale-up facilities by closely mimicking commercial production environments while reducing the consumption of Active Pharmaceutical Ingredients (API). This simulator is instrumental in collecting extensive data that supports Pharma 4.0 initiatives, facilitating rapid development of scalable Process Analytical Technology (PAT) models, and enabling the creation of digital twins. Widely used by leading pharmaceutical innovators, FFSim™ significantly decreases API usage, accelerates process development, and supports Quality by Design and PAT approaches for achieving blend and content uniformity. An example dataset involves the use of FFSim™ with Near Infrared spectroscopy to develop a Partial Least Square calibration model for APAP blends, showcasing high accuracy in predicting blend uniformity even with complex blends. This simulator aids in generating reliable, scalable NIR models and ensuring quality consistency in pharmaceutical manufacturing processes.