InVivo BioTech Services GmbH a BRUKER Company products

At InVivo, your recombinant antibody production is in reliable hands. Recombinant antibodies for target screening, antigen production or drug discovery can be produced either by transient expression or from your own stable cell line in small to large scales. Transient expression is performed using our in house system InVEST. InVEST guarantees an approximately 80 fold increase in yield compared to commercially available systems, at reduced costs. Within the last 20 years, our experts have acquired significant expertise by producing all kinds of antibodies from humans, rat or mouse. We are ready for the challenge and look forward to working with your hard-to-express proteins!

InVivo is your partner for custom monoclonal antibody production from hybridoma cell lines. More than 3,500 different hybridoma clones producing human, rat, or mouse antibodies have been processed in our lab during the last 20 years. Your challenging clone is in good hands with us supported by special equipment and many years of know-how. Our facilities allow the production of up to 1 kg monoclonal antibodies for use in research, human in-vitro diagnostic, preclinical development, veterinary diagnostics, food and feed safety. Proprietary serum-free media and optimized processes like high cell density fermentation guarantee a production at highest cost-effectiveness.

Transient gene expression in mammalian cells provides reasonable amounts of recombinant proteins and antibodies which is sufficient for most applications. Nevertheless, when it comes to bulk productions for in vitro diagnostics or pre-clinical studies for biopharmaceutical development, the required amount of biological material often exceeds the yield that can be obtained through transient approaches. In this case, production from stable cell lines is highly advantageous since it allows easy generation of larger quantities of recombinant proteins and antibodies in measures of up to several grams per batch.