Refine by
Neurodegenerative Technology
12 companies found
Technologybased inVerona, ITALY
At Sibylla Biotech, we face the complexity of drug discovery with the power of an innovative approach for meeting unmet medical needs. Born out of a scientific challenge, the PPI-FIT protocol (Pharmacological Protein Inactivation by Folding ...
The PPI-FIT (Pharmacological Protein Inactivation by Folding Intermediate Targeting) technology, of which Sibylla is the exclusive licensee, is a paradigm shift in rational drug design. The basic task of drug design is to find a small molecule able ...
Technologybased inWhite Plains, NEW YORK (USA)
Oligomerix is a biotechnology company focused on developing disease-modifying and treatment therapeutics for neurodegenerative diseases characterized by aberrant tau protein ranging from rare tauopathies such as progressive supranuclear palsy ...
There exist numerous rare diseases that tau dysfunction is associated with known as tauopathies. While Alzheimer’s is the largest tauopathy, other tauopathies are rare diseases that present accelerated regulatory pathways and significant ...
Technologybased inOxford, UNITED KINGDOM
Oxford Brain Diagnostics Ltd is rethinking how brain health is assessed and managed. Founded in neuropathological and neuroimaging expertise, the company’s patented Cortical Disarray Measurement (CDM) technology uses MRI brain scan data to support ...
The challenge: Dementia - A Global Healthcare Crisis. Our breakthrough technology is helping us to rethink the way brain health is ...
Technologybased inDallas, TEXAS (USA)
Vaxxinity is a U.S.-based global biotechnology company pioneering a new class of medicines to democratize health. Headquartered in Dallas, TX, with operations in the United States, Latin America, Europe and Asia, the company’s proprietary technology ...
Targets toxic forms of aggregated α-synuclein in the brain to fight Parkinson’s and other synucleinopathies, such as dementia with Lewy Body (“DLB”) and multiple system atrophy (“MSA”). The first part of a Phase 1 ...
Technologybased inProvidence, RHODE ISLAND (USA)
A spinout of Oxford University, founded by a global team of experienced entrepreneurs, technologists, and neuroscientists, ni2o is continuing the work started by MIT’s Mind Machine Project – developing a revolutionary brain-computer interface (BCI) ...
Technologybased inMonterey, CALIFORNIA (USA)
Vybion has pioneered vectorized Intrabodies, the delivery of functional antibody fragments in the scFv format to cells using Adeno associated virus (AAV). The Company has Orphan Drug Designation from the FDA for INT41 to treat Huntington’s disease a ...
INT41 has received Orphan Drug Designation from the FDA for Huntington’s disease. IND enabling studies for INT41 Gene Therapy for Huntington’s disease are in place following a preIND meeting with the FDA in in February 2022 in response ...
Technologybased inBingham, MICHIGAN (USA)
In 2017, a group of internationally-recognized MRI industry professionals and entrepreneurs founded SpinTech, Inc. with the goal of transforming advanced MRI techniques, previously reserved only for the research realm, into practical applications to ...
Technologybased inViken, SWEDEN
TIKOMED AB is a privately owned company based in Viken, Sweden. It is governed by the Laws of the Kingdom of Sweden and was formed in accordance with the Swedish Company Act in 2002. We develop and commercialize innovative treatments for patients ...
ILB’s mechanism of action may either reduce the triggers that lead to cell death or prevent further pathology even if triggers are present. By addressing the underlying processes of disease, ILB could significantly improve outcomes for people ...
Technologybased inMarseille, FRANCE
Neuron Experts is a Contract Research Organization (CRO) specialized in the study of neuro-active compounds. The company uses its own tests based on primary neuronal cell cultures modeling neurodegenerative diseases and neuronal impairment-induced ...
Advice in the preclinical development of new neuro-active compounds. The Neuron Experts team (operational and scientific) provides support and advice in your R&D programs and also in the development of new molecules in specific disease ...
Technologybased inBethesda, MARYLAND (USA)
Gain Therapeutics is redefining drug discovery with its SEE-Txâ„¢ target identification platform. By identifying and optimizing allosteric binding sites that have never before been targeted, Gain is unlocking new treatment options for ...
Krabbe disease is a severe neurodegenerative disorder caused by mutations in GALC, the gene that encodes the galactosylceramidase (GALC) enzyme. These mutations cause GALC misfolding and dysfunction, which leads to the toxic buildup ...
Technologybased inLynnwood, WASHINGTON (USA)
Kurve Therapeutics drug delivery technology is designed to target the most difficult part of the treatment process - getting medication through the blood-brain barrier and into the brain. Kurve Therapeutics has 18 peer-reviewed publications of ...
Technologybased inNes-Ziona, ISRAEL
Kadimastem is a bio-pharmaceutical company that develops industrial regenerative medicine therapies based on differentiated cells derived from Human Embryonic Stem Cells (hESCs) to treat neuro-degenerative diseases such as ALS and Diabetes. ...
Clinical grade human astrocytes (the nervous system supporting cells) for the treatment of ALS and other neurodegenerative diseases. Received approval by the Israeli Ministry of Health to commence our phase I/IIa clinical trial in ...