KM Biologics Co. Ltd. products

An inactivated quadrivalent split (HA) seasonal influenza vaccine produced using embryonated chicken eggs. The vaccine contains 15 μg or more of HA proteins for each strain per adult dose. The strains used to make the vaccine are decided by the MHLW each year.

A hepatitis A vaccine produced by culturing hepatitis A virus on African green monkey kidney GL37 cells, followed by purification and inactivation. Aimmugen was developed in Japan. It is lyophilized and contains no adjuvants. Aimmugen can be administered subcutaneously or intramuscularly to people of all ages. General immunization requires 3 administrations, however, when rapid immunization is needed, 2 administrations at 0 and 2 weeks may be adequate.

In additions to protective antigens against Bordetella pertussis, diphtheria toxoid and tetanus toxoid, Quattrovac also contains inactivated poliovirus types 1, 2 and 3 derived from Sabin strains. Quattrovac does not contain thimerosal or other preservatives, and is provided in an easy to use syringe.

Bimmugen contains hepatitis B virus surface antigens (HBs antigen) prepared from yeast using recombinant technology. Bimmugen can be used not only to prevent hepatitis B infection, but also to prevent maternal transmission and for post-exposure prophylaxis.