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Summary:
Non-union of bone fractures can cause pain and disabilities. Amongst certain fracture types, in specific age groups, the incidence of non-union is over 8% in the United States and over 3.6% of all fractures in the UK. Fracture non-unions have lifelong consequences and a debilitating impact in patients` life. Bone-grafts, allografts and xenograft are currently used to treat bone fractures; however, they have limitations. To overcome these limitations, we herein p