Lumencor products

The Lumencor VOLTA Scanner is an advanced optical high-throughput plate reader designed for performing precise transmembrane ion-channel analyses. This system facilitates the detection and functional analysis of transient cellular processes at sub-millisecond temporal resolution, accommodating both 96 and 384 microwell plates. Utilizing a dual-laser optical system, the VOLTA Scanner provides simultaneous stimulation and detection, ideal for kinetic assays of cellular activity. A typical application involves pharmacological safety profiling, such as detecting drug-induced QT prolongation using voltage-sensitive dyes that reveal changes in transmembrane voltage with 0.1 msec resolution. The instrument enables robust fluorescence analysis, aligning with electrophysiological patch-clamp studies' precision, yet offers more stability and efficiency. The VOLTA Scanner is particularly significant for drug discovery applications, allowing comprehensive characterization of pharmacokinetics and ion-channel interactions under various conditions.