services

Protein Modeling and Target Prioritization By applying MolSoft`s acclaimed ICM modeling tools we can build three-dimensional models and fully evaluate several candidate target genes.

Once a client has a lead compound, MolSoft provides a number of different services to optimize the drug-like properties of the compound/

Cheminformatics solutions are commonly applied during the lead qualification and optimization process as it applies to small molecules and proteins. Molsoft`s Cheminformatics applications include structural analysis, simulation and molecular libraries. Molsoft in a collaboration with Biovitrum AB, Sweden, is co-developing a Cheminformatics Client System using Molsoft`s proprietary programming languages and libraries. This product, called BeeHive, is already being used by Biovitrum and the Structural Genomics Consortium as a program manager and database interface for chemical searches, analysis, and integration. We also provide services for developing custom database and information management systems. For example, we recently developed the ChemDiv`s Chemistry on Demand E-Shop.

The highly specialized research environments of life science industries require an experienced understanding of the drug discovery process. Many prescription drugs are the result of small molecules that were synthesized in large combinatorial libraries and tested ad hoc against potential targets. This random approach requires substantial capital investment and yields a minimal number of potential drug candidates. As an alternative to performing traditional high throughput screening, Molsoft`s Virtual Ligand Screening methodology can conduct in silico high throughput screening of multi-million vendor or combi-chem compound libraries while experimentally testing only a few hundred or thousand of candidates.