N8 Medical, LLC products

Ceragenins are synthetic small molecules that can be manufactured in large scale and, unlike endogenous antimicrobial peptides, are not subject to proteolytic degradation. Over 100 ceragenins have been synthesized to date. Ceragenins consist of a sterol backbone with amino acids and other chemical groups attached to them. These compounds have a net positive charge that is electrostatically attracted to the negatively charged cell membranes of certain bacteria, fungi and viruses.

N8 Medical is pursuing wound closure devices with ceragenins incorporated that leverage their anti-inflammatory and would healing properties.

N8 Medical’s initial product will be a ceragenin-eluting CeraShield™ endotracheal tube designed to address a myriad of complications in mechanically-ventilated patients. These patients often develop respiratory infections, which can lead to sepsis and multi-organ failure.

N8 Medical is pursuing a novel, enhanced dermal filler product with ceragenins incorporated, designed to address key concerns in the dermal filler market.