NeuraLace Medical articles

Abstract
Background. Peripheral nerve injury can result in the formation of neuroma/nerve entrapment, a persistent peripheral neuropathic pain state which is often refractory to invasive interventions or medications. Therefore, there is a need in the field of pain management to develop innovative noninvasive therapy in treating post-traumatic peripheral neuropathic pain states. A new intervention, transcutaneous magnetic stimulation (tMS), is derived from the use of tran

INTRODUCTION

After a peripheral nerve injury, fast conducting large myelinated afferent A-bcta fiber transmission diminishes over time. On the other hand, firing of smaller pain transmitting fibers such as A-dclta and C-fibcrs is enhanced. This aberrant afferent neuronal behavior is thought to be one of the main neuronal mechanisms leading to development of chronic posttraumatic peripheral neuropathic pain (PTP-NP) [Puig and Sorkin, 1996). Clinically, this persistent