Nuvonis products

Vero cells have been used for producing viral vaccines for humans ever since microcarrier- based cell culture processes were developed in the 1970s. WHO has recommended the use of well characterized cell substrates back in 1998 (WHO Technical Report Series 878; Expert Committee on Biological Standardization). Due to its stability and well-documented performance regarding the quality and quantity of viral yield, Vero cells are widely accepted by Regulatory Authorities incl. FDA and used for commercial vaccine production.

Nuvonis has developed continuous avian cell lines from quails, as these lack most of the endogenous retroviral sequences detectable in chicken families. For immortalization and development of the cell line, no viral sequences and no foreign genes were introduced. Therefore, the cell line is not regarded as being genetically modified (GMO).