Pion products

The Scissor N3 is an advanced in vitro model designed to simulate the subcutaneous injection of biopharmaceuticals. This device is particularly useful during the formulation development phase, enabling researchers to perform rank ordering of formulations and excipient screening. It allows for a thorough understanding of how a drug behaves post subcutaneous injection and its subsequent release, thus reducing the dependence on less accurate animal models. This system offers a bio-relevant environment where researchers can observe precipitation events and correlate them to lymphatic and systemic release rates, saving both time and costs in drug development. The Scissor N3 is compatible with the Rainbow R6 in-situ fiber optic UV-vis spectrometer for real-time data collection and an optional fraction collector for offline analysis. The system supports various extracellular matrices, including ECM A and ECM-XR, providing flexibility for testing immediate and sustained release formulations. This technology ensures more reliable and earlier selection of promising formulation candidates.