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Preclinics GmbH services
Camelid VHH Service
Camelid antibodies possess some unique features among mammalian immunoglobulins. Their heavy-chain antibodies lack the light chain and therefore can be used to develop recombinant single-domain antibodies (VHH fragments) with several benefits: Small size: With a molecular weight of approximately 15 kDa, Easier production, High stability: As there is only one protein chain, correct refolding after physical stress keeps the functionality.We can immunize your target of interest: proteins, coupled peptides & haptens, cells, and DNA. We have used different adjuvants to enhance the immune response. We also offer additional services like heavy-chain IgG-specific immune response testing to better predict the success of VHH development. We are capable of producing small or large scale. So we can provide the right amount for your project. Blood, serum, and plasma can be produced in bulk quantities. PBMCs or immunoglobulins can be isolated in large batches.
