Salutaris Medical Devices, Inc. (SMD) products

SalutarisMD [SMD] is a clinical stage medical device company.  SMD`s BetaCurve is a globally-patented, 510(k)-cleared device designed to treat various ophthalmic diseases with precision beta radiotherapy, including PCV. The BetaCurve™ curves around the back of the eye to precisely deliver therapeutic beta radiation to the diseased area using a fiber optic light source for placement guidance. The procedure is a outpatient, takes 10-minutes, and requires only one treatment. Utilizing a common technique, retina surgeons do not require additional methodological training.

Effective against classic wet-AMD caused by VEGF that affects mostly Caucasians 

Choroidal Neovascularization (CNV), the underlying cause of wet-AMD, appears to have multiple pathogenic mechanisms beyond VEGF. Classic capillary CNV is VEGF induced and responds best to anti-VEGF therapy. In contrast, arteriolor CNV seen in minimally classic and occult lesions appear less responsive to anti-VEGF monotherapy, suggesting alternative pathogenesis.

We expect our pivotal trial to show efficacy against wet-AMD with non-VEGF pathogenisis that most often affects darkly pigmented eyes aa