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In surgical tissue recovery, focus is on controlling infection, managing inflammation, and ensuring wound closure. Beneath the surface—anatomically and biologically— the extracellular matrix (ECM) is undergoing remodeling ensure long-term tissue integrity. The ECM is a dynamic, biologically active network that orchestrates the entire process of tissue repair, remodeling, and regeneration after surgery. The ECM’s role in healing is the bidirectional, continuous interaction be
Robert Bearden
Hip fractures are common, especially in older adults, and require timely medical and surgical intervention. These injuries can significantly impact a patient’s mobility, quality of life, and overall health. Hip fractures are a medical emergency, and delayed treatment can lead to severe consequences. Elderly patients are particularly vulnerable to complications from prolonged immobility, such as pressure sores, muscle atrophy, and infections.
The mortality after hip fracture in a
Animesh Agarwal
Posterolateral Rabbit Spinal Fusion Study
I. Introduction
Autologous bone has long been the gold standard for bone graft substitute in spinal fusion procedures. The limited supply and morbidity associated with using autologous graft material led to the development of alternative bone grafting materials. Bioactive glass has a long history of biomedical use and has been shown to facilitate mineral deposition in vitro2,3. In order to take
Background
CellRight Technologies® has developed ACTIGEN™ Verified Inductive Bone Matrix, a dehydrated, verified inductive matrix that may be hydrated with saline, blood, Bone Marrow Aspirate (BMA), Platelet Rich Plasma (PRP), or other cellular components in accordance with a physician’s well-informed medical judgment. The clinician may add allograft or autograft to ACTIGEN™ Verified Inductive Bone Matrix and hydrate the grafting material to the
What is biofilm?
Biofilms are defined as communities of micro-organisms attached to a surface, or one another, and encased within a matrix of extracellular polymeric substance (EPS). The EPS makes up the largest component of the biofilm, and in the biological environment is generally composed of polysaccharides, proteins, glycolipids, blood products, cellular debris, extracellular enzymes, metal ions and extracellular DNA. ¹ It protects the bacteria within, allowing
Susan Dieter
