SoftGenetics, LLC. software

NextGENe software is the perfect analytical partner for the analysis of desktop sequencing data produced by Illumina® iSeq, Miniseq, MiSeq, NextSeq, HiSeq, and NovaSeq systems, Ion Torrent Ion GeneStudio S5, PGM, and Proton systems as well as other platforms. NextGENe software runs on a Windows® Operating System, which provides a biologist-friendly ‘point & click’ interface. It does not require scripting or other bioinformatics support, which are often required when using programs such as CLC Genomics Workbench, Lasergene`s SeqMan Pro, as well as academic software such as MAQ & SOAP, Top Hat, BWA & Bowtie.

Variant Interpretation * Variant Tracking * Coverage Confirmation Save Time & Resources * Compatible with data from all NGS systems * Targeted Panels and Whole Exome Sequencing. Developed in collaboration with the Laboratory Medicine, Information Technology, and Health Science Research departments of Mayo Clinic, Geneticist Assistant NGS Interpretative Workbench is a unique tool for the management, control, visualization, functional interpretation, and knowledge database of next-generation sequencing whole exome data for the purpose of identifying pathogenic variants. Geneticist Assistant may also be used to target specific gene panels.

NextGENeLR Software is an effective and easy-to-use resource for the analysis of long read sequencing data such as data from Pacific Biosciences RS, RSII, Sequel, and Sequel II systems, as well as Oxford Nanopore MinION. NextGENeLR can be used for structural variation detection, STR expansion analysis, and whole genome mitochondrial DNA analysis, including low frequency SNV and indel detection, structural variation detection, and mitochondrial haplotyping, with support for mixed samples. Analyses can be set up using an intuitive interface which facilitates batch processing of a number of samples. Recent enhancements to instruments such as PACBIO® and Oxford Nanopore Technologies have improved accuracy to as much as 98%.