Sun Diagnostics LLC products

Dextran Sulfate has a variety of laboratory applications, including use in preparing a precipitating reagent for the determination of HDL Cholesterol. Dextran Sulfate from Sun Diagnostics, LLC is available in 5-gram bottles, Part Number DS109-5G. Contact Sun Diagnostics for information on bulk quantities.

Manufacturers and clinical laboratories are doing a reasonably good job assessing endogenous interferents that may alter lab test results. The next big hurdle is the assessment of interference from common drugs. There are literally hundreds of drugs in clinical use, both prescription and over-the-counter, which can vary widely in their blood and urine concentrations and which can introduce errors in laboratory testing. Which are the most important to test? An expert panel was convened to make specific recommendations concerning the drugs and concentrations that should be assessed when validating laboratory tests.

Immunoassays are subject to interference from endogenous antibodies, especially human anti-mouse antibodies (HAMA) and rheumatoid factor (RF). The use of murine (mouse) monoclonal antibodies in both diagnostic and therapeutic procedures has resulted in a high prevalence of individuals with detectable human anti-mouse antibodies (HAMA) levels. Circulating HAMA can interfere with clinical assays resulting in false positive or false negative results.