Sutro Biopharma Inc. products

Sutro’s cell-free expression technology provides a rapid and powerful platform for the discovery and development of antibodies that bind simultaneously to two separate antigens (bispecific antibodies).

Sutro’s cell-free expression technology provides a rapid and powerful platform for the discovery and development of next generation antibody-drug conjugates (ADCs).

Sutro’s cGMP multi-product manufacturing facility, located in San Carlos, CA, utilizes single use and stainless steel technologies for fermentation, cell-free expression, and purification of Drug Intermediate and Drug Substance.

Conventional methods for expressing proteins utilize cell lines originating from bacteria, yeast, insects, plants, or mammals. Because these methods require intact, functioning cells, the biochemical and biophysical parameters under which proteins are produced using these methods are inherently limited, often failing to produce many proteins and biologics. Using cell-based expression systems to produce protein variants is also a cumbersome way to enable selection of the best therapeutic candidates.