4 products found

Symple Surgical Inc. products

Direct Ablate Renal Denervation System

Through comprehensive thermal simulation and laboratory testing, Symple Surgical has optimized the DirectAblate Renal Denervation SystemTM to deliver therapeutic microwave energy to the site of the Sympathetic Nerves. Figure 1 shows Computer Generated Thermal Simulation data of the DirectAblate Renal Denervation SystemTM. Figure 2 is histological sample of an in vivo study performed with the DirectAblate Renal Denervation SystemTM. The treatment zone is nearly identical in size and shape to the computer based modeling as identified with NBT viability staining (blue/purple coloring is preserved tissue; translucent/white is treated tissue; rings are 1mm spacing).

Directed Renal Denervation (dRDN)

The Symple Surgical microwave device is demonstrated within a protein albumin gel highlighting the “doughnut-shape” circumferential ablation zone created. While penetrating 6mm deep in to the protein gel, the test demonstrates the thermal protection of the vessel wall and the 1mm ring of the medial layer. Past the 6mm ablation zone there is a substantial drop-off in temperature, thereby limiting damage to the non-target perivascular structures.

DirectAblate Renal Denervation System

A secondary product is the DirectAblate Renal Denervation System^TM which is a proprietary self-centering internally integrated microwave antenna, real-time surface temperature monitoring, and active arterial wall cooling for safety. A 100 Watt / 2.45 GHz microwave generator with integrated control system provides precise control and data acquisition. DirectAblate Renal Denervation System^TM has superior catheter and energy delivery technology that effectively delivers a single 90 second circumferential non-contact ablation per renal artery.

The Symple Surgical

The Symple Surgical GRIZZLY^TM microwave ablation catheter system is a beside-the-scope, over-the-wire, moveable antennae, compliant urethane balloon system. The catheter is a fully automated system that can create complete circumferential and spot ablations from a single device up to 40mm in length. A compliant urethane balloon provides the ability to target esophagus diameters between 18-35mm. Initial product offering will be a beside-the-scope catheter with .035 guidewire compatibility. At the heart of the GRIZZLY^TM catheter is a proprietary microwave antenna which paired with the 50W, 18GHz microwave generator delivers precise and uniform microwave energy to the target ablation zone.