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Fucosylates Hematopoietic and Progenitor Stem Cells
TZ 102, like all of TargaZyme’s therapeutics, is an off-the-shelf product for point-of-care use. It’s made of two (2) components, fucosyltransferase VII enzyme and GDP Fucose.
Fucosylation Technology Platform
The therapeutic value of any cell-based therapy is highly dependent on the ability of cells to reach the diseased organ to exert their therapeutic function. Our core technology – ex vivo fucosylation – enhances the physiological mechanism by which cells circulating in the blood stream reach the diseased tissue. This mechanism is triggered by the interaction between selectins (P and E-selectins) found on the lining of blood vessels and epithelium of a multitude of tissues such as the bone marrow and certain cell-surface biomolecules to which a sugar (fucose) is enzymatically added by fucosylation.
