Troikaa Pharmaceuticals Ltd. products

Dynapar AQ is a novel Diclofenac injection manufactured by the Aquatech Process, which provides the full dose of 75 mg Diclofenac in just 1 ml. The Aquatech process provides the optimal concentration of Diclofenac in an aqueous solvent system, thereby, providing the full therapeutic dose in a smaller volume.

Dynapar QPS is the world`s first Transdermal preparation of Diclofenac, which provides excellent pain relief after topical application, by enhancing the penetration of Diclofenac through the skin. Dynapar QPS is backed by proof of concept pharmacokinetic studies as well as clinical trials.

Phlebotroy QPS is used in prevention and treatment of thrombophlebitis. Phlebotroy QPS is a new generation topical solution which ensures higher penetration of Heparin as compared to conventional ointment/gel. It is backed by multicentric clinical trials and is manufactured using the globally patented QPS technology. Each ml of Phlebotroy QPS contains 1000 lU/ml of Heparin Sodium.

NASOMAX technology is a proprietary nasal drug delivery technology for safe and effective systemic delivery of the drug molecule, through the nasal route. Methylcobalamin has very low solubility in water. To provide optimum therapeutic benefit by the nasal route, Methylcobalamin is dissolved at 500 meg per 0.1 ml concentration, in a solvent system consisting of safe, non-irritating co-solvent which enhances absorption of Methylcobalamin rapidly through the nasal membrane.

Sevotroy is a perfect Anti-HF formulation with optimum water content advantage. Sevotroy is indicated for induction and maintenance of general anaesthesia in adult and paediatric patients for inpatient and outpatient surgery. To prevent degradation of Sevoflurane to Hydrofluoric acid, Troikaa has developed Sevotroy formulation having the optimum water content. It is manufactured in Troikaa`s state-of-the-art manufacturing facility that ensures zero impurity. Even the impurities permissible in the U.S. Pharmacopoeia are absent in Sevotroy.

Troypofol is an emulsion injection of Propofol and is manufactured by Nanoemulsion Technology. It is manufactured in an ultramodern facility equipped with a high-speed homogenizer which ensures control on globule size of the emulsion. Troypofol Nanoemulsion Technology results in small, uniform and controlled globule size of Troypofol Nanoemulsion which provides better efficacy of Troypofol and less incidence of pain.

Cyanide Antidote Kit is used for the treatment of cyanide poisoning. The kit provides a dose of amyl nitrite for inhalation and an intravenous sodium nitrite injection. This converts a portion of the haemoglobin`s iron from ferrous iron to ferric iron, converting the haemoglobin into Methaemoglobin. 

To provide therapeutically meaningful extended delivery of drugs, Troikaa has developed Duo Phase Technology. Through this technology, the drug dose is split judiciously into two components, where one part delivers the drug immediately and the other releases the drug in a sustained release pattern. Thus drug delivery is biphasic and ensures the requisite pharmacokinetic profile. Drugs developed using this technology are extended-release Paracetamol tablets of 650 mg and 1000 mg (Xykaa Extend). Products manufactured using Duo Phase Technology are presented in stylized tablets which graphically represent the biphasic drug delivery.

Intra oral drug delivery provides an excellent route of drug delivery into the systemic circulation. It has inherent advantages such as the prompt onset of action & predictable drug delivery. Trofentyl OTFC is a lozenge of Fentanyl Citrate for the treatment of breakthrough pain. As soon as the patient rolls the lozenge in his/her oral cavity, the drug released from the lozenge gets absorbed from the oral mucosa. The pain relief starts in about 10-12 minutes and lasts for 20-25 minutes. In the event the patient experiences any adverse effects, he/she can simply take the lozenge out and the effect will wear off in a few minutes.

Decompaction Technology ensures quick decompaction of granules to micro-fine particles, resulting in faster absorption and a quicker onset of action. Products manufactured using this technology are very useful in those conditions where a rapid onset of action is desirable. Currently, the two products manufactured using this technology are Dynapar Tablets (Diclofenac + Paracetamol) & Xykaa Rapid (Paracetamol). When ingested, the active drug is ready for absorption in just 45 seconds and hence provides assured relief in less than 20 minutes.