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Container Closure Integrity Deterministic & Quantitative Testing Solutions
ZebraSci - Residual Seal Force & Parenteral Vial Capping
Residual Seal Force (RSF) is a non-destructive method to evaluate seal tightness in the stopper/seal combination of parenteral vials. Parenteral vial systems consist of a vial, a stopper and an overseal. Capping parameters are a critical aspect during drug product manufacturing. During the sealing process, improper capping can generate cosmetic defects or worse yet, impact Container Closure Integrity (CCI). Process development and capping optimization can help reduce risk associated with the capping process.
