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Zurex Pharma, Inc. articles
Abstract
Background: An innovative approach to perioperative antiseptic skin preparation is warranted because of potential adverse skin irritation, rare risk of serious allergic reaction, and perceived diminished clinical efficacy of current perioperative antiseptic agents. The results of a confirmatory US Food and Drug Administration (FDA) phase 3 efficacy analysis of a recently approved innovative perioperative surgical skin antiseptic agent are discussed.
M
Charles Edmiston;Philip Lavin;Maureen Spencer;Gwen Borlaug;Gary Seabrook;David Leaper
Abstract
Objective: Alternatives to skin preparation with conventional preoperative antiseptics are required because of adverse reactions and the potential emergence of resistance. Here, we present 2 phase 2 studies of ZuraGard (ZG), a novel formulation of isopropyl alcohol and functional excipients developed for preoperative skin antisepsis.
Methods: Microbial skin flora on abdominal and inguinal sites in healthy volunteers were quantitatively assessed follow
Christopher Crnich;Aurora Pop-Vicas;Thomas Hedberg;Trish Perl
