Nexelis - Model Alpha-1 - Microglobulin - Brochure

Alpha-1 microglobulin is member of the lipocalins superfamily of proteins with 30–35 members distributed among animals, plants, and bacteria. The members of the superfamily have a highly conserved three-dimensional structure.  So far, three lipocalins have been shown to be enzymes.  These include alpha-1 microglobulin, which was recently shown to have reductase/dehydrogenase properties.  Also called protein HC, alpha-1 microglobulin is one of the first described lipocalins and is one of the most widespread lipocalins phylogenetically.  So far, it has been found in mammals, birds, fish, and amphibians.