Bacterial Strains Articles & Analysis: This-Year
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Conducted in accordance with OECD Guidelines for Testing of Chemicals, Test No. 471, the bacterial reverse mutation test (Ames) uses histidine-dependent strains of Salmonella typhimurium or Escherichia coli to detect permanent gene mutations (e.g., single or multiple base pair substitutions, insertions or deletions) caused by new chemicals and candidate drugs. ...
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