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Nucleic Acid Articles & Analysis: Older
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It is adaptable for a wide range of therapeutic modalities, including small molecules, antibodies, and nucleic acids. With this proprietary platform, Ace Therapeutics is developing and partnering on next-generation BBB transporter services to address the formidable challenge of the blood-brain barrier. ...
The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client ...
Tailored Carriers: Polymers and dendrimers for sustained and targeted release. Nucleic Acid Delivery: One-stop mRNA/siRNA formulation and scale-up. ...
These extracellular vesicles have a phospholipid bilayer structure and can carry important biological information, such as proteins, nucleic acids (e.g., microRNA and long non-coding RNA), and lipids. These extracellular vesicles, composed of cell membranes, can attach to target cells through surface adhesion proteins and carrier ligands, such as tetrapeptides, ...
In many research applications, such as gene expression studies, vaccine development, and gene therapy, transfection—the process of introducing nucleic acids into cells—is an essential step. Despite the advances in transfection technologies, choosing the appropriate reagents for particular cell types and experimental conditions can be difficult for ...
The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client ...
Nucleosides, the building blocks of nucleic acids, aren’t only simple building blocks for RNA and DNA. ...
For accurate quantification of nucleic acids, techniques such as quantitative PCR (qPCR) or digital droplet PCR (ddPCR) are recommended, particularly for determining the final library quantity. ...
This strategic move is aimed at addressing the rising global demand for Lipid Nanoparticles (LNPs), which are vital for nucleic acid drug delivery, especially in mRNA-based therapies and vaccines. ...
The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client ...
BOC Sciences, the world-leading chemical manufacturer and technical solution provider, recently added a series of exosome technologies to meet diverse needs in nucleic acid delivery. Exosomes are tiny vesicles secreted by cells, capable of transporting molecules from one cell to another. ...
Biotinylation, a widely used biological technique, involves the covalent attachment of biotin to biomolecules such as proteins, peptides, and nucleic acids. This technique plays a crucial role in various research fields, including molecular biology, biochemistry, and diagnostics. ...
They can be used for the delivery of small molecule drugs, biologics, vaccines, and even nucleic acids. By bypassing the gastrointestinal tract and avoiding first-pass metabolism, microneedle-based drug delivery allows for higher bioavailability and improved therapeutic outcomes. ...
By introducing bacteriophage SP6 into the transcriptional promoter and a completely artificial E01 sequence selected from a randomized nucleic acid sequence pool into the translational enhancer, an mRNA with high translational activity can be produced, and protein synthesis efficiency can be maximized. ...
The biological reagents previously launched by Alfa Chemistry encompass transilluminator, proteomic products (i.e., Protein Marker/Ladder, Western Substrate, Protein Staining Reagent, OneStep Blocker, UltraScence TMB ELISA Substrate), genomic products (i.e., DNA Marker/Ladder, Staining Reagent, Agarose, PCR Reagent, RNA Reagent, Real-Time PCR Reagent), and nucleic ...
Both appointments come as etherna’s new strategy is gaining significant traction globally. etherna is enabling a growing number of life science and pharma companies to accelerate their pursuits into the fast-growing nucleic acid sector by leveraging the Company’s industry-leading proprietary RNA-based chemistry, its custom LNP delivery platforms, and ...
ByeTheRNA
Traditional nucleic acid detection methods require trained operators and sophisticated instrumentation, with signal reading and detection times often taking hours. ...
These chemicals have inclusive applications in mRNA vaccines and therapeutics, RNA therapeutics (ASO, siRNA, miRNA, Aptamer), nucleic acid detection, gene sequencing and editing (CRISPR-Cas9), and oligonucleotide synthesis, etc. ...
The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client ...
Everyone unanimously approved and applauded the exhibited products which included the PreMed 5200 liquid chromatography tandem mass spectrometry system, GeneTOF 3100 nucleic acid mass spectrometry system, ClinCap 1000 fully automated capillary electrophoresis instrument, and MSFLO benchtop mass spectrometry flow cytometer among a few.Focusing on clinical ...