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MiLaboratories LLC launches TCR profiling for non-human primates

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Nov. 7, 2020
Courtesy ofMi Laboratories

Service available for rhesus macaque (Macaca mulatta) and cynomolgus (crab-eating macaque, Macaca fascicularis). Phylogenetic closeness to humans makes non-human primates a model of choice for assessing the safety and efficiency of novel monoclonal antibodies and immunotherapeutic approaches. UMI-based TCR profiling allows to track the clonotype fates and alterations in TCR repertoire with the highest precision. Such analysis has become a tool of choice for in-depth monitoring of changes in the immune system in response to a certain therapy. High accuracy of our analysis helps practitioners to comply with modern ethical standards by reducing the required number of animals.