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MedChemExpress - Model Quercitrin -522-12-3
Quercitrin (Quercetin 3-rhamnoside) is a bioflavonoid compound with potential anti-inflammation, antioxidative and neuroprotective effect. Quercitrin induces apoptosis of colon cancer cells. Quercitrin can be used for the research of cardiovascular and neurological disease research[1][2].MCE products for research use only. We do not sell to patients.
Quercitrin
MCE China：Quercitrin
Brand：MedChemExpress (MCE)
Cat. No.HY-N0418
CAS：522-12-3
Synonyms：Quercetin 3-rhamnoside
Purity：99.72%
Storage：-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Shipping：Room temperature in continental US; may vary elsewhere.
Description：Quercitrin (Quercetin 3-rhamnoside) is a bioflavonoid compound with potential anti-inflammation, antioxidative and neuroprotective effect. Quercitrin induces apoptosis of colon cancer cells. Quercitrin can be used for the research of cardiovascular and neurological disease research.
In Vitro：Quercitrin (5-50 μM; 24-72 h) time- and dose-dependently inhibits cell proliferation and increases cytotoxic effects to colorectal carcinoma cells[1]. Quercitrin (5-50 μM; 24-72 h) time- and dose-dependently increases nucleosomal enrichment factor (EF) of DLD-1 cells[1]. Quercitrin (50 μM; 48-72 h) induces cell apoptosis and the loss of mitochondrial membrane potential, and causes translocation of phosphatidylserine (PS) from the inner to outer Leaflet of DLD-1 cells[1].
In Vivo：Quercitrin (50 and 100 mg/kg; oral gavage, once) shows effective protection against brain injury in mice by inhibiting oxidative stress and inflammation induced by carbon tetrachloride[2].
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References：
[1]. Cincin ZB, et al. Apoptotic Effects of Quercitrin on DLD-1 Colon Cancer Cell Line. Pathol Oncol Res. 2015 Apr;21(2):333-8. [Content Brief]
[2]. Cincin ZB, et al. Apoptotic Effects of Quercitrin on DLD-1 Colon Cancer Cell Line. Pathol Oncol Res. 2015 Apr;21(2):333-8. [Content Brief]
Brand introduction:
• MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world；
• More than 50,000 highly selective inhibitors and agonists are involved in various popular signaling pathways and disease areas；
• The products cover a variety of recombinant proteins, peptides, commonly used kits, more PROTAC, ADC and other characteristic products, widely used in new drug research and development, life science and other scientific research projects；
• Provide virtual screening, ion channel screening, metabolomics analysis detection analysis, drug screening and other professional technical services；
• It has a professional experimental center and strict quality control and verification system；
• Provide LC/MS, NMR, HPLC, chiral analysis, elemental analysis and other quality inspection reports to ensure the high purity and high quality of products；
• The biological activity of the products has been verified by the experiments of customers in various countries；
• A variety of top journals such as Nature, Cell, Science and pharmaceutical patents have included the scientific research results of MCE customers；
• Our professional team tracks the latest pharmaceutical and life science research and provides you with the latest active compounds in the world；
• It has established long-term cooperation with the world's major pharmaceutical companies and well-known scientific research institutions。