DRG - Anti Ovarian Ab ELISA
The DRG Anti Ovarian Ab ELISA is an enzyme immunoassay for the quantitative in vitro diagnostic measurement of antibodies directed against oocytes in human serum.
Antibodies directed against oocyte antigens may cause infertility in women. The application of the Anti Ovarian Ab ELISA may serve as an aid for the diagnosis of immunologically caused disorders of fertility or premature ovarian failure (1).
Auto-antibodies against oocyte antigens have been shown to be associated with poor ovarian response to controlled ovarian hyperstimulation (2). Furthermore, autoimmunity is responsible for approximately 4-30% of premature ovarian insufficiency (POI) (3) and is associated with polycystic ovary syndrome (PCOS) (4-6).
Unwanted childlessness is a growing problem with which up to 20% of all couples in the reproductive age are confronted temporarily or long-term.
The definition of infertility according to the WHO (WHO Laboratory Manual for the Examination of Human Semen and Semen Cervical-Mucus Interaction, 1999) is the absence of a conception within 12 months of unprotected intercourse.