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AntibodiesInc - Model 75-048 -Anti-WAVE1/SCAR Antibody
Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human cerebral cortex [HBM(Cx)] or hippocampus [HBM(H)] and probed with K91/36 (left) or N52A/42 (right) TC supe.
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- Clonality: Monoclonal
- Applications: IHC, IP, WB
- Host Species: Mouse
- Gene Name: WASF1 KIAA0269 SCAR1 WAVE1
- Molecular Weight: 75 kDa
- Target: WAVE1/SCAR
- Target Description: Wiskott-Aldrich syndrome protein family member 1, Verprolin Homology Domain-Containing Protein 1, Protein WAVE-1 or SCAR1 is encoded by the gene WASF1 and is a member of the Wiskott-Aldrich syndrome protein (WASP)-family. WAVE1/SCAR is an effector protein which transmits of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. WAVE1/SCAR acts as part of the WAVE complex which is involved in the regulation of actin filament reorganization and membrane ruffling. WAVE1/SCAR is expressed in many tissues including brain, ovary, colon, kidney, pancreas and thymus. Diseases associated with this gene include Wiskott-Aldrich Syndrome and Alacrima, Achalasia, And Mental Retardation Syndrome.
- Format: Purified
- Concentration: 1 mg/mL
- Clonality: Monoclonal
- Clone: K91/36
- Antibody Isotype: IgG1
- Applications: IHC, IP, WB
- Host Species: Mouse
- Gene Name: WASF1 KIAA0269 SCAR1 WAVE1
- Molecular Weight: 75 kDa
- Antigen: Synthetic peptide amino acids 477-498 of human Wave1/Wasp family 1(CQVIPASEPKRHPSTLPVISDAR; accession number Q92558); Rat: 95% identity (21/22); Mouse=95% identity (21/22)
- Species Reactivity: Human, Mouse, Rat
- Antibody Registry ID: AB_2216976
- Storage: Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
- Physical State: Liquid
- Conjugate: Unconjugated
- Specificity: No cross-reactivity reported
- Usage Statement: These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
- Country of Origin: United States
- Expiration: 24 months from opening
- Synonyms: Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1)
- UniProt Details: UniProt (Human): Q92558; UniProt (Immunogen Species): Q92558