Autoimmune diseases are due to inappropriate immune response against the organism’s own antigens (autoantigens), leading to chronic inflammation, tissue destruction and/or dysfunction. Generally unknown by the public and perceived as uncommon, they represent nevertheless the third cause of clinical mortality in industrialized countries.

According to the estimation of the World Health Organization, they affect up to 6 % of the global population. Scientists and doctors agree that more than 60 diseases have a proven or strongly suspected autoimmune cause. Moreover, there is epidemiological evidence of increasing prevalence of certain autoimmune diseases, which cannot be attributed to focus on or improvement of the diagnosis alone.

As the autoimmune diseases are generally incurable and require a lifelong treatment they have a strong impact on public health cost. Their accurate diagnosis has therefore become of major importance these last decades. All the diagnosis techniques available on the market are based on the ability to detect the presence of autoantibodies in the patient’s serum.

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