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Ankyrons - Binding to Therapeutic Antibody Idiotypes
Anti-Idiotype Ankyrons a game-changer for developing assays to track target-specific antibodies. Take the pain out of targeting the idiotype of your antibodies. Detecting and targeting specific antibody idiotypes is key for developing effective tracking assays for drug antibodies. Developing monoclonal and eventually recombinant anti-drug idiotype antibodies for such purposes has been possible but time-consuming and expensive.
Ankyrons provide a clear and powerful solution to this problem. Selected directly in vitro from our Teralibrary we already offer a growing range anti-drug idiotype Ankyrons, including against already approved therapeutic antibodies for Herceptin® (trastuzumab), Erbitux® (cetuximab), Avastin® (bevacizumab), Humira® (adalimumab), and Rituxan® (rituximab). Using guided selection we are able to select idiotype-specific Ankyrons quickly confirming non-binding to unrelated drug antibodies and other Ig subtypes.
