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  • tagraxofusp

Tagraxofusp Medical Equipment & Supplies

1 equipment items found

Tagraxofusp - Novel Targeted Therapy

Tagraxofusp - Novel Targeted Therapy

Manufactured by:The Menarini Group   based inFlorence, ITALY
TAGRAXOFUSP is a novel targeted therapy directed to the IL-3 receptor α (CD123), a target present on a wide range of malignancies including Blastic Plasmacytoid Dendritic Nell Neoplasm (BPDCN). It comprises human IL-3 recombinantly fused to a truncated diphtheria toxin (DT) payload engineered such that IL-3 replaces the native DT receptor-binding domain. The IL-3 domain of TAGRAXOFUSP ...
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