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BOC Sciences - Model CAS 34157-83-0 -Celastrol (Tripterine)
FromBOC Sciences
Celastrol (tripterine) is a chemical compound isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments, celastrol exhibits antioxidant, anti-inflammatory, anticancer, and insecticidal activities. It has been shown to have obesity-controlling effects in mice.
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Chemical Information
- Category: Drug Discovery
- Molecular Formula: C29H38O4
- Molecular Weight: 450.61
- Brife Description: Celastrol(Tripterin) is a novel Hsp90 inhibitor.It is also a potent antioxidant and anti-inflammatory agent.
- Purity: >98%
- Related CAS: 34157-83-0 (castrol) 193957-88-9 (dihydrocelastrol)
- Appearance: Red powder
- Synonyms: Tripterine
- Solubility: DMSO > 10 mM
- Storage: 3 years -20oC powder, 6 months-80oC in solvent.
- MSDS: Material Safety Data Sheet-Celastrol 34157-83-0
- Quality Standard: In-house
- Quantity: Grams-Kilos
- Melting Point: 195 °C
- InChI Key: KQJSQWZMSAGSHN-JJWQIEBTSA-N
- InChI: InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
- Canonical SMILES: CC1=C(C(=O)C=C2C1=CC=C3C2(CCC4(C3(CCC5(C4CC(CC5)(C)C(=O)O)C)C)C)C)O
