JD Bioscience Inc. (JDB)
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JDBDrug Candidate for Heart Disease

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JDB is developing a novel drug candidate for heart disease that can rescue heart function at a cellular level, and can eventually help improving heart function.

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  • Heart disease, a leading cause of death globally, can be categorized into ischemic heart disease, cardiomyopathy, and myocarditis.
  • Different types of medication are available to treat heart disease, for example, cholesterol-lowering medications, beta-blockers, nitroglycerin, and calcium channel blockers. However, none of these can rescue the function of cardiomyocytes once heart failure is in progression.
  • Ischemic heart disease is involved in the reduction of blood flow due to the accumulation of fatty deposits in the coronary arteries. Cardiomyopathy, including hypertrophic or dilated cardiomyopathy, is a disease of the heart muscle that can occur due to various risk factors. Finally, myocarditis is characterized by the inflammation of the heart muscle, which often occurs due to a viral infection. All of these can ultimately lead to fatal heart failure.