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Fluxion - Model NGS - Spotlight Liquid ...

Fluxion - Model NGS -Spotlight Liquid Biopsy Panels

FromFluxion Biosciences Inc

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Ultra-sensitive somatic mutation detection from liquid biopsy samples. Designed specifically for detection of mutations from liquid biopsy samples, Spotlight Oncology Panels are turnkey solutions for Illumina sequencers, offering ultra-sensitive variant detection from low input quantities of DNA. The high sensitivity of Spotlight panels makes them ideal for cfDNA, CTCs, and other challenging sample types such as FFPE. Incorporating ERASE-Seq, Fluxion’s statistically powered variant caller, Spotlight delivers unrivaled sensitivity in liquid biopsies.

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CUSTOM PANEL DEVELOPMENT

Fluxion offers customized Spotlight Panels optimized to enable fast, comprehensive targeted sequencing. Combined with ERASE-Seq bioinformatics, this unique approach provides a powerful solution for detecting ultra-low frequency somatic mutations using low-input DNA from cfDNA. To get started with a custom Spotlight panel, fill out the custom panel design template and submit to info@fluxionbio.com.

SPOTLIGHT PANELS FEATURE...

Detection to <0.05% allele frequency
Average specificity >99.999%
Ready-to-sequence libraries in just 2 hours
Starting input quantities as low as 10 ng DNA
Average amplicon size of 140 bp for compatibility with cfDNA and FFPE
No molecular barcodes (unique molecular IDs) required; increases sensitivity, reduces bias and assay complexity
ERASE-Seq data analysis included with kit purchase