GRAFIX PL, by Smith+Nephew, Inc.
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GRAFIX PLUSPlacental Membrane for Chronic Wound Management

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GRAFIX PLUS Placental Membrane is designed for advanced wound management, focusing on treating chronic wounds. This product leverages human placental membranes, which are minimally manipulated to retain their native cells, growth factors, and extracellular matrix, ensuring the preservation of structural integrity. The membrane comprises three essential components of the placental structure, emphasizing the collagen-rich matrix crucial for wound healing. GRAFIX PLUS uses cutting-edge preservation techniques that help maintain the integrity of the native amniotic membrane, offering optimal conditions for tissue regeneration. The meticulous processing of the membrane helps enhance clinical outcomes by addressing the biological needs of the chronic wound environment. This product is primarily intended for professional use by caregivers in the U.S., aiding in complex wound care strategies where conventional treatments may fall short.

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Minimal manipulation to maximize retained components

Advanced preservation methods that minimize manipulation of the native amniotic membrane and retain all three native components of human placental membranes, including native placental cells.

Why GRAFIX PL and GRAFIX Cryopreserved Placental Membrane?

Our human placental tissue products, carefully processed to minimize manipulation of the native tissue, are composed of native cells, growth factors, and an intact extracellular matrix.

  • to wounds and compromised surgical sites
  • Flexible, conforming covers that may be applied over bone, tendon, and other structures
  • Available in two storage options:
    • GRAFIX PL Membrane is lyopreserved and stored at room temperature for off-the-shelf convenience
    • GRAFIX Membrane is cryopreserved and stored at -75°C to -85°C