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Boston Pharmaceuticals
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Boston - Model BOS161721 - Avizakimab -Human Anti-IL-21 Antibody

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BOS161721 (avizakimab) is a fully human anti-IL-21 antibody.

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  • IL-21 plays a central role in systemic lupus erythematosus (SLE) through B- and T-cell mediated autoimmunity and generation of autoantibodies to nuclear antigens, a disease hallmark in SLE.
  • BOS161721 (avizakimab) demonstrated safety, tolerability, target engagement and pharmacological activity in a Phase 1 study in healthy volunteers (HV).