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Virpax Drug Interaction Equipment & Supplies
2 equipment items found
Manufactured by:Virpax Pharmaceuticals based inBerwyn, PENNSYLVANIA (USA)
Since peripheral exposure via the plasma will be reduced by the nose to brain delivery, we believe there will be negligible liver first-pass metabolism. NobrXiol may not be metabolized in the liver avoiding drug to drug interactions caused by oral pharmaceutical-grade CBD. By avoiding the first pass effect Intranasal NobrXiol may eliminate ...
Manufactured by:Virpax Pharmaceuticals based inBerwyn, PENNSYLVANIA (USA)
Endogenous peptides with analgesic potential include endorphins via binding to the mu receptor, dynorphins via the kappa receptor and enkephalins via the delta receptor. Kappa and delta opioid agonists have been shown to provide analgesic benefit while sparing mu agonist toxicity1. Preclinical data supports analgesia from enkephalin without significant opioid tolerance or drug liking. Typically, ...