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Sumitomo Leukemia Aml Equipment & Supplies

1 equipment items found

Sumitomo - Model DSP-5336 - Menin-MLL Binding Inhibitor

Sumitomo - Model DSP-5336 - Menin-MLL Binding Inhibitor

by:Sumitomo Pharma Oncology, Inc.   based inCambridge, MASSACHUSETTS (USA)
DSP-5336 is a small molecule inhibitor against the binding of menin and mixed-lineage leukemia (MLL) protein. Menin is a scaffold nuclear protein that plays various key roles in biological pathways, including cell growth regulation, cell cycle control, genomic stability, bone development, and hematopoiesis.26,27 Binding of menin to MLL fusion and wildtype proteins leads to the upregulation of ...
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