ReproNovo - Model RPN-001 (Leflutrozole) -Male Infertility Therapy System

With our lead product candidate, RPN-001 (leflutrozole), the focus of our clinical research is on treating infertile men with low serum testosterone. RPN-001 is a novel molecular entity with the potential to enhance spermatogenesis. By inhibiting the aromatase enzyme, leflutrozole suppresses the conversion of testosterone to estradiol, thereby normalizing testosterone levels and rebalancing the testosterone to estradiol ratio. Additionally, it stimulates the production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These effects lead to improved testicular function and increased spermatogenesis.