Theradaptive - Material-Binding Proteins Engineering Technology
With our innovative protein-engineering technology, we transform proteins into material-binding variants.
Our computational platform converts recombinant proteins into material-binding variants that can be used to coat implants, devices, and injectable carriers. This novel and unprecedented method enables us to deliver therapeutics to any location in the body with precision.
NATIVE PROTEIN
Proteins in nature did not evolve specifically to treat diseases. Most proteins administered as therapeutics to patients have suboptimal properties for treating the target disease.
PROPRIETARY SEQUENCE OPTIMIZATION
With a combination of computational and in vitro methods we are able to identify variants that have valuable material binding properties.
MATERIAL-BINDING VARIANTS
The output of this process is a novel protein variant that preserves native biological function and that can bind to the selected material with extremely high affinity. This enables new therapeutics that are safer and more effective.
ONE-STEP SURFACE COATING
Our modified proteins can be applied easily in a simple one-step process that does not require any chemical modification.
BINDING WITH ANY CARRIER
Our material-binding proteins can be used to coat implants, devices, and injectable carriers. Carriers coated with our modified proteins enable long-term local delivery with vastly reduced off target effects.