BioFire FilmArray - Model ME -Meningitis/Encephalitis Panel
Distinguishing bacterial from viral meningitis based on clinical presentation is challenging. Patients often present with similar, flu-like symptoms.
The BioFire ME Panel tests for a comprehensive set of 14 of the most common bacterial, viral, and fungal pathogens associated with central nervous system (CNS) infections in about one hour using only 0.2 mL of cerebrospinal fluid (CSF).4
THE BIOFIRE ME PANEL MENU
Overall 94.2% Sensitivity and 99.8% Specificity
Sample Type: Cerebrospinal Fluid (CSF)
BACTERIA:
- Escherichia coli K1
- Haemophilus influenzae
- Listeria monocytogenes
- Neisseria meningitidis
- Streptococcus agalactiae
- Streptococcus pneumoniae
VIRUSES:
- Cytomegalovirus (CMV)
- Enterovirus (EV)
- Herpes simplex virus 1 (HSV-1)
- Herpes simplex virus 2 (HSV-2)
- Human herpesvirus 6 (HHV-6)
- Human parechovirus (HPeV)
- Varicella zoster virus (VZV)
- CSF cultures may take >48 hours for organism identification and are positive in 70-85% of patients with bacterial meningitis who have not received prior antimicrobial therapy; therefore rapid diagnostic tests should be considered to determine the bacterial etiology of meningitis.
- PCR may be useful for excluding the diagnosis of bacterial meningitis, with the potential for influencing decisions to initiate or discontinue antimicrobial therapy.
- Rapid PCR detection of enterovirus may lead to shorter hospital stays and decreased use of antimicrobial therapy.
- >10% of patients with viral encephalitis can have normal CSF findings. Additional CSF tests, such as PCR, should be performed to establish the specific cause of encephalitis.
- Acyclovir should be initiated in all patients with suspected encephalitis.
- In patients who have negative herpes simplex 1 and 2PCR results, do not modify treatment, repeat testing.
Decreasing time to result can help improve patient outcomes. Don’t lose another minute. Get results in about one hour with the BioFire ME Panel.
Find Meningitis/Encephalitis Faster. Treat it Sooner.While traditional meningitis tests take 24–48 hours, the BioFire ME Panel uses PCR technology to go from sample to results in about one hour.
One hour.Add the BioFire ME Panel as a first line test and get answers in a clinically-actionable time frame.
- Simple: 2 minutes of hands-on time
- Easy: No precise measuring or pipetting required
- Fast: Turnaround time of about one hour
- Comprehensive: 14 bacterial, viral, and fungal targets