Panagene Inc.

PNAClampModel IDH1 - Mutation Detection Kit

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Mutations of IDH1 (isocitrate dehydrogenase 1,IDH1) can be found in glioblastoma and myeloproliferative neoplasm. Detection of IDH1mutations can be a positive predictor of a prognosis and a molecular marker for glioblastoma patients. On the other hand, it is reported that IDH1 mutations correlate with poor prognosis in myeloproliferative neoplasm. PNAClamp™ IDH1 Mutation Detection Kit is a new member of somatic mutation detection kits utilizing PNA-mediated PCR Clamping technology, and can help patients choose the right medicine and monitor prognosis.

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  • FFPE tissue
  • Fresh tissue
  • sample preparation
  • Extraction of Total DNA
  • Amplification of target DNA by Real-Time PCR
  • Analysis of Result
  1. High sensitivity and specificity even with small amount of DNA (1% LOD with 10 ng wild/mutant type mixed DNA)
  2. Real-Time PCR based ready-to-use kit
  3. Short running time (within 3 hours)