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Precision - Model NxGen -Scalable Genetic Medicine Formulation
NxGen simplifies and accelerates genetic medicine development by enabling all scales through one single mixing element. NxGen achieves this unique scalability by preserving the critical conditions at the point of formulation regardless of whether the throughput is mL/min or L/hour.
The proprietary NxGen microfluidic mixer at the heart of NanoAssemblr systems is designed specifically for genetic medicine development. Our Classic (formerly known as SHM) mixer was developed to address issues of reproducibility with scale-up achieved by scale-out of parallel mixers. NxGen, however, is uniquely capable of more than 25x throughput of our Classic mixer while maintaining the signature particle formation conditions that ensure the most reproducible results for a wide range of particle types.
The NxGen mixer enables the reproducible scale-up of mRNA Lipid Nanoparticles and other complex nanomedicine formulations
- Test batches of up to 20 L/h produced with a single NxGen mixer
- Particle characteristics (size and PDI) are constant
- Biological activity maintained