TIB - Model p16 - Protein/Ki-67 Dual Staining Kit for Cell Cycle and Lesion Detection

The p16 protein/Ki-67 Dual Staining Kit offered by Triplex International Biosciences is designed to aid in the evaluation of cellular proliferation and potential disruptions in the cell cycle. The kit employs two key biomarkers: the p16 protein, a cyclin-dependent kinase inhibitor that plays a critical role in the regulation of the cell cycle, and Ki-67, a known marker for cell proliferation which is expressed primarily during the mitotic phase. The overexpression of p16 can occur due to the disruption of cellular processes driven by the integration of HPV and host genes, which leads to uncontrolled proliferation. Simultaneous detection of both p16 and Ki-67 in cervical epithelial cells serves as a crucial indicator of abnormal cellular proliferation and potential lesions. This ready-to-use kit features vibrant color indicators, a long shelf life, and convenient storage conditions. Additionally, it includes necessary cytological consumables for ease of use in laboratory settings.