QuantideX - qPCR BCR-ABL minor Kit (RUO)
The QuantideX® qPCR BCR-ABL minor Kit (RUO) is a clinical research tool enabling ultra-sensitive and precise detection of BCR-ABL1 minor fusion transcripts (e1a2) from whole blood specimens. Building on the simple workflow and best-in-class sensitivity established with the FDA-cleared QuantideX® qPCR BCR-ABL IS Kit, the minor Kit allows labs and clinical researchers to examine the biology of disease for this very rare but distinct leukemic variant with unprecedented ease.
The QuantideX qPCR BCR-ABL minor Kit (RUO) delivers high performance through unmatched sensitivity and optimized laboratory efficiency.
Reduced Complexity
Ease-of-data analysis and reporting:
- Leverages the QuantideX® qPCR BCR-ABL IS Kit workflow concept for streamlined implementation
- QuantideX qPCR Reporter provides automated calculation of BCR-ABL1/ABL1 % ratio and eliminates the need for manual calculation
Optimized Workflow
Valuable operator hands-on time has been significantly reduced through:
- Multiplexed design amplifies and detects both fusion and control gene in the same reaction
- All-inclusive reagents sourced and quality controlled together from a single vendor
- Pre-mixed reagents allow fewer pipetting steps in mastermix preparation
Quality Performance
Detecting BCR-ABL1 minor transcripts robustly and reliably with a highly sensitive assay:
- Ultra-sensitive Limit of Detection (LOD): Log reduction of 4.61 (0.0025% ratio)
- Increased analytical sensitivity without compromising analytical specificity: incorporates Limit of Blank (LOB) to prevent miscalling of non-leukemic low positives
- Armored RNA®-based standards provide true RNA quantification