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XstrahlModel SARRP -Small Animal Radiation Research Platform for Preclinical Studies

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The Small Animal Radiation Research Platform (SARRP) by Xstrahl is a cutting-edge system designed for preclinical radiation research. SARRP is notable for its ability to replicate modern radiation therapy techniques within a laboratory setting, offering researchers the tools to conduct precise, clinically relevant studies. It includes an integrated Motorized Variable Collimator, which allows for conformal radiation techniques with dynamic jaws capable of adjusting field sizes extensively. The platform also features a 360° gantry and motorized stage for non-coplanar beam delivery, enhancing the accuracy of dose application while reducing damage to non-targeted tissues. Additionally, SARRP’s advanced software integration supports various treatment planning solutions, accommodating simple to complex beam arrangements. Its use is predominantly in academic and research institutions, where it plays a pivotal role in image-guided studies, DNA repair mechanisms, and fostering collaborations. With installations worldwide, SARRP assists in translating clinical practices into experimental research, thereby enriching scientific insights into radiation therapy.

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SARRP Replicates Modern Radiation Therapy Systems

SARRP enables investigators to perform clinically relevant radiation research in a preclinical setting. It is the only commercially available system that includes an integrated Motorized Variable Collimator (MVC) so researchers can perform conformal radiation therapy techniques commonly used in clinical practice. Dynamic jaws allow investigators to dictate field sizes ranging from 1mm x 1mm, up to 40mm x 80mm, so that it is easy to perform both small and large field irradiation. The 360° gantry and motorized stage allow for non-coplanar beam delivery from any angle, resulting in a more 3D conformal dose to the target area, while drastically minimizing normal tissue and surrounding tissue toxicity.

Advanced Treatment Planning Software

SARRP’s open system integration offers researchers flexibility to select from several treatment planning solutions to create and deliver simple or complex beam arrangements in a clinically relevant way. Techniques utilizing planar static beams, parallel opposed beams, continuous arc therapies, multiple isocenter treatments, and non-planar arcs can all be planned, evaluated, and delivered with SARRP. Even researchers with little to no knowledge of radiation therapy are able to easily plan and execute studies using either SmART-XPS or Muriplan.

SARRP Brings Success & Fosters Collaboration

SARRP is the first choice of researchers worldwide for translational radiation research. Diverse groups – including academic institutions, research hospitals, CROs, and countless interdisciplinary teams – conduct successful image-guided studies using SARRP. More than 85% of published studies are performed using SARRP. These investigators value integrated tools, such as:

  • Motorized Variable Collimator
  • Imaging Panel – 25cm x 20cm
  • Monte Carlo Planning Algorithm
  • Heated Mouse Bed
  • 4D Treatment Head