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- Spotlight - Model TP 53 - Liquid Biopsy ...
Spotlight - Model TP 53 -Liquid Biopsy Panel
The Spotlight TP53 liquid biopsy NGS panel contains 21 amplicons with an average size of 140 bp that provides comprehensive coverage of all coding regions of TP53. The Spotlight TP53 Panel is compatible with short DNA fragments from cfDNA and FFPE samples. This product is a complete kit that includes all elements necessary for generating ready-to-sequence libraries, including primer pairs and indexed sequencing adapters. Combined with ERASE-Seq, Fluxion`s statistically powered variant caller, Spotlight 59 delivers >90% sensitivity and
Spotlight TP53 is powered by ERASE-Seq, Fluxion`s statistically powered variant caller that is available free of charge to Spotlight users. ERASE-Seq utilizes statistical analysis to compare sequencing results to a detailed background model and technical replicates. This approach eliminates both random errors and systemic biases inherent in all sequencing workflows. ERASE-Seq delivers superior detection sensitivity to 0.1% allele frequency and below, with a false positive rate 10-100X lower than leading molecular barcode approaches.
