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Kangstem Biotech Co., Ltd.
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  5. Furestem - Model AD Inj - Stem Cell ...

Furestem - Model AD Inj -Stem Cell Therapeutic Product for Atopic Dermatitis

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FURESTEM-AD Inj. is the world’s first stem cell therapeutic product for atopic dermatitis that targets moderate to severe atopic dermatitis patients.

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  • Product name : FURESTEM-AD® Inj.
  • Manufacturer : Kangstem Biotech
  • Target : Moderate to severe atopic dermatitis patients
  • Injection route : Subcutaneous injection

MoA : IL-4 is secreted from Th2 cells. FURESTEM-AD® Inj. is stimulated by IL-4. Stimulated FURESTEM-AD® Inj. secretes TGF-ß1. TGF-ß1 suppresses expression of FceR1 receptor (during maturation of mast cells). FURESTEM-AD® Inj. secretes PGE2. PGE2 suppresses degranulation of mast cells. FURESTEM-AD® Inj. inhibits each step of mast cell activation and degranulation through the secretions of TGF-ß1 & PGE2.